Dow Jones
51,554.97
Change
+31.91+0.06%
52-Week Top Gaining U.S. stocks
Track U.S. stocks with the strongest price gains over the past 52 weeks on MEXC. Stocks are ranked by their 52-week percentage change to highlight leading one-year performers.
Market Overview
U.S. stocks are mixed today. The Dow Jones is +0.06%, the S&P 500 is +0.86%, and the Nasdaq Composite is +1.58%. Across individual stocks, 2,215 are advancing while 2,902 are declining, suggesting a mixed market tone.
S&P 500
7,416.73
Change
+63.0+0.86%
Nasdaq Composite
24,699.493
Change
+384.496+1.58%
24H Gainers
2,215
24H Losers
2,902
52 Week Gainers
| # | Stock | 52 Week Range | |||||
|---|---|---|---|---|---|---|---|
| 1 | Eloxx Pharmaceuticals, Inc.ELOX | $12.78 | +0.32% | 7.06K | $51.59M | $12.62 - $23.40 | 0.00% |
| 2 | Mega Fortune Company LimitedMGRT | $119.98 | +1.06% | 2.04K | $1.65B | $4.04 - $170.00 | 0.00% |
| 3 | Bank of New York Mellon CorporationBNY | $148.85 | +0.85% | 693.85K | $100.16B | $10.05 - $165.84 | 0.02% |
| 4 | Nine Energy Service, Inc.NINE | $7.05 | +0.15% | 15.07K | $104.21M | $0.29 - $13.23 | 0.00% |
| 5 | TJGC Group LimitedTJGC | $31.64 | -3.18% | 68.09K | $319.51M | $1.46 - $36.76 | 0.00% |
| 6 | Moderna, Inc.MRNA | $263.78 | +9.57% | 10.55M | $105.31B | $22.28 - $273.72 | 0.00% |
| 7 | BUUU Group LimitedBUUU | $5.17 | +3.02% | 34.77K | $1.39B | $0.57 - $8.10 | 0.00% |
| 8 | agilon health, inc.AGL | $108.99 | -5.18% | 75.64K | $1.83B | $7.48 - $133.04 | 0.00% |
| 9 | Erasca, Inc.ERAS | $13.74 | +3.69% | 1.01M | $4.81B | $2.10 - $24.28 | 0.00% |
| 10 | Kodiak Sciences Inc.KOD | $98.31 | +7.25% | 206.00K | $6.18B | $15.83 - $104.00 | 0.00% |
| 11 | CareDx, Inc.CDNA | $78.17 | +3.18% | 506.87K | $4.11B | $14.58 - $90.87 | 0.00% |
| 12 | Space Exploration Technologies Corp.SPCX | $132.24 | +6.08% | 54.37M | $1.92T | $21.32 - $225.64 | 0.00% |
| 13 | Climb Bio, Inc.CLYM | $9.95 | +11.33% | 291.69K | $571.49M | $1.64 - $18.33 | 0.00% |
| 14 | SELLAS Life Sciences Group, Inc.SLS | $7.94 | +1.52% | 4.86M | $1.60B | $1.39 - $15.88 | 0.00% |
| 15 | Avita Medical, Inc.RCEL | $16.47 | +5.42% | 519.75K | $506.89M | $3.22 - $17.82 | 0.00% |
| 16 | Vince Holding Corp.VNCE | $12.63 | +2.34% | 102.66K | $163.47M | $1.95 - $13.88 | 0.00% |
| 17 | 10x Genomics, Inc.TXG | $58.80 | +0.52% | 2.07M | $7.07B | $12.80 - $102.81 | 0.00% |
| 18 | Spyre Therapeutics, Inc.SYRE | $100.97 | +4.54% | 405.28K | $10.29B | $21.14 - $110.17 | 0.00% |
| 19 | Fossil Group, Inc.FOSL | $7.96 | +2.64% | 474.82K | $470.56M | $1.70 - $8.02 | 0.00% |
| 20 | AXT Inc.AXTI | $38.19 | +4.55% | 7.07M | $2.50B | $7.81 - $143.16 | 0.00% |
| 21 | New Century Logistics (BVI) LimitedNCEW | $17.27 | +5.82% | 23 | $55.28M | $2.80 - $20.83 | 0.00% |
| 22 | STAK Inc.STAK | $2.70 | +45.81% | 6.56M | $29.39M | $0.29 - $12.00 | 0.00% |
| 23 | Anterix Inc.ATEX | $74.27 | +5.27% | 61.31K | $1.46B | $17.58 - $113.00 | 0.00% |
| 24 | Sandisk CorporationSNDK | $838.82 | +4.20% | 10.64M | $160.29B | $183.00 - $2,354.39 | 0.00% |
| 25 | Q32 Bio Inc.QTTB | $9.30 | +5.54% | 76.29K | $276.77M | $1.91 - $23.57 | 0.00% |
| 26 | Twist Bioscience CorporationTWST | $120.73 | -0.06% | 882.99K | $7.57B | $23.30 - $219.71 | 0.00% |
| 27 | PACS Group, Inc.PACS | $49.14 | -1.93% | 257.18K | $7.78B | $10.31 - $51.68 | 0.01% |
| 28 | ImmunityBio, Inc.IBRX | $8.20 | +2.87% | 3.21M | $8.69B | $1.95 - $12.43 | 0.00% |
| 29 | OmniAb, Inc.OABI | $5.12 | +5.69% | 307.01K | $747.10M | $1.33 - $5.43 | 0.00% |
| 30 | Alpha Tau Medical Ltd.DRTS | $13.93 | +1.80% | 112.19K | $1.26B | $3.43 - $15.79 | 0.00% |
| 31 | Veradermics, IncorporatedMANE | $136.02 | +6.16% | 196.30K | $5.58B | $32.00 - $146.57 | 0.00% |
| 32 | Oruka Therapeutics, Inc.ORKA | $100.18 | +4.98% | 201.75K | $6.63B | $25.23 - $115.52 | 0.00% |
| 33 | AN2 Therapeutics, Inc.ANTX | $3.96 | +0.25% | 16.32K | $149.32M | $1.00 - $7.19 | 0.00% |
| 34 | Iovance Biotherapeutics, Inc.IOVA | $7.96 | +3.10% | 4.82M | $3.61B | $2.08 - $15.37 | 0.00% |
| 35 | Nuvectis Pharma, Inc.NVCT | $19.43 | +10.28% | 41.11K | $634.27M | $5.55 - $29.27 | 0.00% |
| 36 | Pulse Biosciences, Inc.PLSE | $52.02 | -4.47% | 154.16K | $3.68B | $12.56 - $63.39 | 0.00% |
| 37 | MaxLinear, Inc.MXL | $47.76 | +7.02% | 1.34M | $4.35B | $12.77 - $128.30 | 0.00% |
| 38 | GIBO Holdings LimitedGIBO | $162.71 | +6.26% | 15.15K | $250.03M | $22.60 - $187.72 | 0.00% |
| 39 | Ampco-Pittsburgh Corp.AP | $6.08 | +3.19% | 30.44K | $125.71M | $1.75 - $12.81 | 0.00% |
| 40 | Quhuo LimitedQH | $2.81 | -1.58% | 1.76K | $7.98M | $0.07 - $12.81 | 0.00% |
| 41 | Revolution Medicines, Inc.RVMD | $189.34 | +7.57% | 1.57M | $40.58B | $58.91 - $224.31 | 0.00% |
| 42 | Rallybio CorporationRLYB | $15.66 | -0.41% | 3.45K | $84.34M | $3.67 - $17.57 | 0.00% |
| 43 | Entravision CommunicationEVC | $8.76 | +16.20% | 1.15M | $726.27M | $2.56 - $13.74 | 0.03% |
| 44 | Tilly's Inc.TLYS | $4.28 | +1.90% | 37.67K | $99.64M | $1.14 - $6.25 | 0.00% |
| 45 | SAIHEAT LimitedSAIH | $21.30 | -4.10% | 3.58K | $25.46M | $5.90 - $33.00 | 0.00% |
| 46 | RF Acquisition Corp IIRFAI | $32.12 | +7.05% | 2.02K | $112.81M | $8.94 - $73.00 | 0.00% |
| 47 | Able View Global Inc.ABLV | $2.66 | +4.31% | 39.35K | $65.22M | $0.54 - $2.96 | 0.00% |
| 48 | Century Therapeutics, Inc.IPSC | $1.59 | +4.97% | 136.07K | $288.82M | $0.43 - $3.04 | 0.00% |
| 49 | American Well CorporationAMWL | $12.07 | -0.83% | 40.12K | $181.86M | $3.71 - $15.16 | 0.00% |
| 50 | Vera Bradley, Inc.VRA | $6.91 | -1.29% | 242.90K | $198.24M | $1.39 - $7.72 | 0.00% |
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Frequently Asked Questions (FAQ)
What are 52-week top gaining U.S. stocks?
These are U.S. stocks with some of the strongest price gains over the past 52 weeks, providing a view of longer-term stock performance.
How is the 52-week gain calculated?
It compares a stock's latest available price with its price roughly 52 weeks earlier and expresses the change as a percentage.
Which stock has gained the most over 52 weeks?
Eloxx Pharmaceuticals, Inc. (ELOX) currently leads with a 52-week gain of 1,228,445.45% as of 2026-11-06 17:16 UTC.
Why use a 52-week stock performance ranking?
It helps users identify stocks with sustained price strength over a longer period rather than focusing only on daily market moves.
Does strong 52-week performance guarantee future gains?
No. Historical stock performance does not determine future returns and should be considered alongside company fundamentals and current market conditions.
How is this different from the daily Top Gainers list?
The 52-week ranking focuses on one-year performance, while Top Gainers highlights shorter-term price movements.
Discover Top US Stocks
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Disclaimer
US stock prices, indices, rankings, charts, and other market data displayed on this page may be sourced from third-party providers and may be delayed or inaccurate. MEXC provides this information for informational and educational purposes only and does not guarantee its accuracy or completeness. Nothing on this page constitutes financial or investment advice or a recommendation to buy or sell any security. US stock trading involves risk, and past performance does not guarantee future results. Users should conduct independent research before making investment decisions.