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52-Week Top Gaining U.S. stocks

Track U.S. stocks with the strongest price gains over the past 52 weeks on MEXC. Stocks are ranked by their 52-week percentage change to highlight leading one-year performers.

52-Week Top Gaining U.S. stocks

Market Overview

U.S. stocks are mixed today. The Dow Jones is ⁦-0.27%⁩, the S&P 500 is ⁦+0.62%⁩, and the Nasdaq Composite is ⁦+1.42%⁩. Across individual stocks, 2,289 are advancing while 2,828 are declining, suggesting a mixed market tone.

Dow Jones
51,385.87
Change
-137.19-0.27%
S&P 500
7,399.3
Change
+45.57+0.62%
Nasdaq Composite
24,660.698
Change
+345.701+1.42%
24H Gainers
2,289
24H Losers
2,828

52 Week Gainers

#Stock52 Week Range
4901Fractyl Health, Inc.GUTS$0.93+3.01%75.62K$11.91M$0.82 - $29.340.00%
4902Concorde International Group LtdCIGL$0.18+5.39%33.45K$37.61M$0.17 - $3.760.00%
4903Callan JMB Inc.CJMB$0.28-2.13%316.40K$2.54M$0.26 - $5.610.00%
4904TNL MediageneTNMG$3.07+4.92%39.12K$2.71M$2.45 - $92.880.00%
4905Capstone Holding Corp.CAPS$1.95+2.91%5.31K$1.79M$1.85 - $34.800.00%
4906CCSC Technology International Holdings LimitedCCTG$0.29+10.69%227.09K$4.52M$0.17 - $5.640.00%
4907NeuroSense Therapeutics Ltd.NRSN$1.40-4.69%9.30K$2.66M$1.10 - $25.400.00%
4908America's Car Mart Inc.CRMT$1.39-7.89%318.60K$11.59M$0.57 - $28.700.00%
4909Adagio Medical Holdings, Inc.ADGM$0.07+8.08%1.08M$1.84M$0.05 - $1.690.00%
4910Innovation Beverage Group LimitedIBG$0.78-3.44%12.54K$3.28M$0.71 - $15.800.00%
4911Sadot Group Inc.SDOT$6.25+2.56%59.77K$9.10M$2.63 - $106.000.00%
4912SurgePays, Inc.SURG$0.16+2.03%1.69M$8.62M$0.11 - $2.920.00%
4913VivoSim Labs, Inc.VIVS$0.14+1.41%152.04K$2.36M$0.14 - $3.400.00%
4914Kandal M Venture LimitedFMFC$2.70-4.90%30.76K$1.81M$2.60 - $46.800.00%
4915Virax Biolabs Group LimitedVRAX$0.80-38.98%963.07K$637.55K$0.65 - $21.750.00%
4916Neo-Concept International Group Holdings LimitedNCI$0.61+3.58%58.72K$2.82M$0.25 - $110.480.00%
4917Smart Powerr Corp.CREG$0.78-47.55%2.83M$0$0.00 - $26.600.00%
4918Beyond Air, Inc.XAIR$2.160.00%16.57K$3.60M$2.05 - $53.200.00%
4919Sports Entertainment Gaming Global CorporationSEGG$1.18-28.92%527.26K$4.04M$1.12 - $32.550.00%
4920Cyngn Inc.CYN$0.26-4.89%263.73K$4.04M$0.25 - $4.470.00%
4921New Fortress Energy Inc.NFE$4.32+12.47%237.43K$24.65M$3.24 - $99.000.02%
4922AIAI Holdings CorporationAIAI$0.93-2.16%272.55K$95.64M$0.84 - $19.570.00%
4923Reviva Pharmaceuticals Holdings, Inc.RVPH$0.000.00%0$0$0.26 - $15.400.00%
4924Gauzy Ltd.GAUZ$6.18-7.11%8.26K$7.07M$4.00 - $103.800.00%
4925Baosheng Media Group Holdings LimitedBAOS$0.16-1.70%32.02K$5.41M$0.15 - $3.820.00%
4926Abits Group Inc.ABTS$0.37-3.94%258.19K$872.16K$0.31 - $6.900.00%
4927Farmmi, Inc.FAMI$0.09+4.31%1.96M$507.62K$0.09 - $1.850.00%
4928Fermi Inc.FRMI$1.52-0.98%20.82M$1.30B$1.44 - $27.070.00%
4929Blaize Holdings, Inc.BZAI$0.20-1.81%1.12M$28.53M$0.17 - $3.670.00%
4930Cellyan Biotechnology Co., LtdHKPD$1.41+7.35%46.44K$4.78M$1.34 - $29.000.00%
4931E-Home Household Service Holdings LimitedEJH$1.21+4.31%2.89K$3.87M$1.01 - $26.500.00%
4932MultiSensor AI Holdings, Inc.MSAI$3.05-3.14%4.49K$6.73M$2.84 - $60.000.00%
4933AirSculpt Technologies, Inc.AIRS$0.59-57.96%8.82M$42.90M$0.56 - $10.630.00%
4934Ping An Biomedical Co., LtdPASW$1.35-14.15%149.33K$15.51M$1.06 - $28.560.00%
4935BioAtla, Inc.BCAB$1.77-42.99%1.01M$0$0.96 - $71.500.00%
4936BioRestorative Therapies, Inc.BRTX$1.52-2.93%9.60K$2.10M$1.28 - $29.300.00%
4937Core AI Holdings, Inc.CHAI$0.18+11.40%448.38K$3.55M$0.16 - $4.050.00%
4938Auddia Inc.AUUD$0.47-19.90%190.20K$2.73M$0.46 - $11.470.00%
4939Gossamer Bio, Inc.GOSS$9.85+2.60%64.99K$60.25M$8.29 - $309.600.00%
4940Vicarious Surgical Inc.RBOT$0.000.00%0$0$0.00 - $5.180.00%
4941Polaryx Therapeutics, Inc.PLYX$1.81+5.17%21.23K$86.23M$1.69 - $48.910.00%
4942HCW Biologics Inc.HCWB$1.03-2.88%20.70K$2.30M$1.01 - $23.940.00%
4943Actuate Therapeutics, Inc.ACTU$0.32-0.28%425.24K$7.68M$0.31 - $7.900.00%
4944Tianci International, Inc.CIIT$2.27+46.13%40.42M$2.20M$1.52 - $52.500.00%
4945Datavault AI Inc.DVLT$0.07+16.05%110.64M$63.54M$0.05 - $2.700.00%
4946Eshallgo Inc.EHGO$1.71+1.49%38.64K$2.95M$1.50 - $35.190.00%
4947Olenox Industries Inc.OLOX$0.69+4.85%90.90K$1.15M$0.60 - $21.900.00%
4948HUHUTECH International Group Inc.HUHU$0.45-5.09%1.35M$11.57M$0.32 - $12.200.00%
4949Singularity Future Technology LtdSGLY$0.39-10.61%150.38K$2.12M$0.30 - $14.280.00%
4950Greenlane Holdings, Inc.GNLN$1.19-2.87%6.15K$823.03K$1.00 - $27.920.00%

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Frequently Asked Questions (FAQ)

What are 52-week top gaining U.S. stocks?
These are U.S. stocks with some of the strongest price gains over the past 52 weeks, providing a view of longer-term stock performance.
How is the 52-week gain calculated?
It compares a stock's latest available price with its price roughly 52 weeks earlier and expresses the change as a percentage.
Which stock has gained the most over 52 weeks?
Fractyl Health, Inc. (GUTS) currently leads with a 52-week gain of 92.87% as of 2026-11-06 20:43 UTC.
Why use a 52-week stock performance ranking?
It helps users identify stocks with sustained price strength over a longer period rather than focusing only on daily market moves.
Does strong 52-week performance guarantee future gains?
No. Historical stock performance does not determine future returns and should be considered alongside company fundamentals and current market conditions.
How is this different from the daily Top Gainers list?
The 52-week ranking focuses on one-year performance, while Top Gainers highlights shorter-term price movements.

Discover Top US Stocks

Disclaimer

US stock prices, indices, rankings, charts, and other market data displayed on this page may be sourced from third-party providers and may be delayed or inaccurate. MEXC provides this information for informational and educational purposes only and does not guarantee its accuracy or completeness. Nothing on this page constitutes financial or investment advice or a recommendation to buy or sell any security. US stock trading involves risk, and past performance does not guarantee future results. Users should conduct independent research before making investment decisions.