Buy Crypto
Markets
Spot
FuturesBTC
Earn
Event Center
Rewards Hub
More

52-Week Top Losing U.S. stocks

Track U.S. stocks with the largest price declines over the past 52 weeks on MEXC. Stocks are ranked by 52-week percentage change from lowest to highest.

52-Week Top Losing U.S. stocks

Market Overview

U.S. stocks are mixed today. The Dow Jones is ⁦-0.46%⁩, the S&P 500 is ⁦+0.31%⁩, and the Nasdaq Composite is ⁦+1.09%⁩. Across individual stocks, 2,319 are advancing while 2,800 are declining, suggesting a mixed market tone.

Dow Jones
51,285.73
Change
-237.33-0.46%
S&P 500
7,376.86
Change
+23.13+0.31%
Nasdaq Composite
24,579.425
Change
+264.428+1.09%
24H Gainers
2,319
24H Losers
2,800

52 Week Losers

#Stock52 Week Range
4351Regeneron Pharmaceuticals Inc.REGN$904.25+0.19%670.87K$91.90B$591.52 - $991.730.00%
4352Fastly, Inc.FSLY$15.90+3.41%9.70M$2.53B$7.87 - $34.820.00%
4353Reinsurance Group of America, IncorporatedRGA$261.91-0.02%610.96K$17.10B$182.73 - $272.440.01%
4354First Northern Community Bancorp.FNRN$17.13-5.34%100$280.77M$12.40 - $19.250.00%
4355Wheaton Precious Metals Corp.WPM$136.30+2.93%1.54M$61.90B$96.14 - $165.760.00%
4356John Wiley & Sons, Inc.WLY$50.26-0.48%211.00K$2.11B$28.38 - $57.450.03%
4357Mirum Pharmaceuticals, Inc.MIRM$93.74+0.16%614.33K$6.09B$63.23 - $130.000.00%
4358GH Research PLCGHRS$18.59+0.87%415.61K$1.28B$12.04 - $31.440.00%
4359QUAD/GRAPHICS, INC.QUAD$7.59-1.04%245.35K$285.70M$5.12 - $11.140.05%
4360Constellium SECSTM$21.81+3.33%1.28M$2.93B$14.62 - $36.990.00%
4361PUMA BIOTECHNOLOGY INC.PBYI$8.25-15.56%1.22M$426.07M$4.58 - $11.500.00%
4362Trio-Tech InternationalTRT$4.70+2.52%55.32K$48.58M$3.25 - $21.380.00%
4363Diana Shipping, Inc.DSX$2.34+0.86%415.38K$291.50M$1.63 - $3.200.00%
4364PROG Holdings, Inc.PRG$37.69-2.96%411.96K$1.47B$25.18 - $47.730.01%
4365Kingstone Companies, Inc.KINS$20.46+7.81%233.98K$296.18M$13.83 - $21.000.01%
4366The Macerich CompanyMAC$24.85-0.72%2.11M$7.05B$16.03 - $26.680.03%
4367Extreme NetworksEXTR$24.02+14.13%4.64M$3.15B$13.47 - $33.730.00%
4368Teleflex IncorporatedTFX$150.87-0.84%756.68K$6.39B$100.18 - $156.670.01%
4369Tenet Healthcare Corporation NewTHC$283.29-1.09%540.00K$22.55B$157.58 - $301.440.00%
4370Host Hotels & Resorts, Inc.HST$24.64-0.02%6.36M$16.88B$16.77 - $26.190.04%
4371Equillium, Inc.EQ$1.52+15.04%213.61K$96.32M$0.76 - $3.540.00%
4372METROCITY BANKSHARES INC.MCBS$36.08+0.06%71.94K$1.04B$24.53 - $37.460.03%
4373Enova International, Inc.ENVA$172.48-1.03%189.86K$4.22B$119.02 - $267.450.00%
4374Reservoir Media, Inc.RSVR$10.19-1.36%50.46K$670.65M$7.07 - $13.390.00%
4375Royal Bank of CanadaRY$201.16-1.28%1.42M$278.41B$143.38 - $218.560.00%
4376Imax Corp.IMAX$47.69-0.96%1.21M$2.62B$32.71 - $57.730.00%
4377KNOWLES CORPORATIONKN$31.24+3.10%870.29K$2.65B$20.57 - $42.930.00%
4378BRC Group Holdings, Inc.RILYG$24.90+0.32%20.80K$0$15.42 - $25.000.00%
4379Bank of MontrealBMO$171.07-0.77%251.19K$118.32B$119.84 - $187.220.00%
4380Mohawk Industries, Inc.MHK$150.49-0.24%971.36K$10.19B$92.99 - $155.880.00%
4381First Community Bankshares, Inc. (VA)FCBC$45.45+0.20%70.38K$859.46M$31.21 - $50.170.05%
4382Peoples Bancorp of North CarolPEBK$41.09-5.21%282.03K$224.39M$29.31 - $45.780.02%
4383PCB Bancorp.PCB$29.98-0.33%16.78K$421.06M$20.87 - $32.000.03%
4384Republic Bancorp Inc/KYRBCAA$91.05-0.09%50.78K$1.59B$63.97 - $102.220.02%
4385Magnera CorporationMAGN$12.34+1.90%253.14K$441.92M$7.82 - $15.520.00%
4386Certara, Inc.CERT$12.04-1.23%4.32M$1.84B$4.45 - $12.610.00%
4387Corvus Pharmaceuticals, Inc.CRVS$10.56+8.53%1.04M$888.23M$6.39 - $26.950.00%
4388Ardagh Metal Packaging S.A.AMBP$4.72-0.84%998.22K$2.82B$3.29 - $5.470.00%
4389CSX CorporationCSX$49.11-3.40%9.41M$90.53B$33.63 - $53.600.01%
4390Sierra Bancorp.BSRR$41.29-1.39%46.48K$535.43M$28.35 - $44.000.03%
4391ARAMARKARMK$52.54+4.45%3.44M$13.85B$35.07 - $62.650.01%
4392UNIVERSAL INSURANCE HLDG, INC.UVE$46.73-1.41%261.54K$1.29B$28.32 - $50.750.02%
4393V.F. CorporationVFC$20.35+0.19%8.99M$8.01B$12.46 - $22.270.02%
4394DXP Enterprises Inc.DXPE$140.50+5.58%282.88K$2.18B$84.04 - $208.000.00%
4395Pricesmart Inc.PSMT$162.49-0.01%140.07K$5.03B$114.38 - $199.840.01%
4396Albany International Corp.AIN$67.20+0.37%131.10K$1.91B$41.15 - $77.000.02%
4397ACNB Corp.ACNB$65.53+0.96%26.97K$666.44M$44.62 - $68.850.03%
4398Kinetik Holdings Inc.KNTK$48.75-0.75%1.04M$3.92B$31.33 - $58.900.01%
4399Algoma Steel Group Inc.ASTL$5.38+8.02%1.88M$568.99M$3.16 - $5.900.00%
4400Alkermes Inc. plcALKS$45.90+3.06%1.29M$7.70B$27.00 - $55.670.00%

Anthropic (PRE): Win NVIDIA H200

Claim PRE points for guaranteed prizes up to $3K

Anthropic (PRE): Win NVIDIA H200

Trade U.S. stocks Your Way on MEXC

RealStocksTokenized StocksStock Futures
What it isRealStocks — real shares of U.S.-listed companiesBlockchain-based tokens linked to U.S. stocks/ETFsUSDT-margined futures on U.S. stock price movements
OwnershipYes — actual sharesNo — synthetic exposure onlyNo — derivative exposure only
Shareholder rightsYes (e.g. dividends)NoNo
Trading hoursU.S. market sessions (pre-market, regular, after-hours, overnight)24/7Up to 24/7 (supported pairs)
Position typesBuy and holdBuy and holdLong, short, leveraged
Best forLong-term investors seeking ownership and dividend incomeTraders wanting round-the-clock access to stock exposure without holding sharesActive/short-term traders looking to speculate or hedge with leverage

Why Trade U.S. stocks on MEXC?

RealStocks, Real Ownership

Buy real US-listed shares through MEXC's partner licensed broker and receive applicable shareholder benefits, including dividends.

7,000+ U.S. stocks & ETFs

Access 7,000+ US-listed stocks and ETFs across technology, finance, healthcare, consumer sectors, and more.

Seamless USDT-to-Stock Access

Transfer USDT and convert between USDT and USD to fund your RealStocks account with ease.

Lower-Cost Stock Trading

Trade real U.S. stocks with competitive costs and keep more capital available for your investment strategy.

Frequently Asked Questions (FAQ)

What are 52-week top losing U.S. stocks?
These are U.S. stocks that have recorded some of the largest price declines over the past 52 weeks.
How is the 52-week decline measured?
It compares the latest available stock price with its price around 52 weeks earlier and calculates the percentage change.
Which stock has fallen the most over 52 weeks?
Regeneron Pharmaceuticals Inc. (REGN) currently shows a 52-week decline of 37.52% as of 2026-11-07 16:52 UTC.
Why track 52-week stock losers?
The ranking helps identify stocks facing prolonged price weakness and provides a starting point for further company and valuation research.
Is a 52-week loser automatically a value stock?
No. A lower stock price does not necessarily mean a company is undervalued, so valuation and fundamental data should be reviewed separately.
How is this different from Top Losers?
52-Week Losers measures longer-term performance, while Top Losers focuses on shorter-term market declines.

Discover Top US Stocks

Disclaimer

US stock prices, indices, rankings, charts, and other market data displayed on this page may be sourced from third-party providers and may be delayed or inaccurate. MEXC provides this information for informational and educational purposes only and does not guarantee its accuracy or completeness. Nothing on this page constitutes financial or investment advice or a recommendation to buy or sell any security. US stock trading involves risk, and past performance does not guarantee future results. Users should conduct independent research before making investment decisions.