Buy Crypto
Markets
Spot
FuturesBTC
Earn
Event Center
Rewards Hub
More

52-Week Top Losing U.S. stocks

Track U.S. stocks with the largest price declines over the past 52 weeks on MEXC. Stocks are ranked by 52-week percentage change from lowest to highest.

52-Week Top Losing U.S. stocks

Market Overview

U.S. stocks are mixed today. The Dow Jones is ⁦-0.46%⁩, the S&P 500 is ⁦+0.32%⁩, and the Nasdaq Composite is ⁦+1.09%⁩. Across individual stocks, 2,308 are advancing while 2,809 are declining, suggesting a mixed market tone.

Dow Jones
51,286.21
Change
-236.85-0.46%
S&P 500
7,376.92
Change
+23.19+0.32%
Nasdaq Composite
24,579.425
Change
+264.428+1.09%
24H Gainers
2,308
24H Losers
2,809

52 Week Losers

#Stock52 Week Range
4551Littelfuse Inc.LFUS$356.18+2.15%215.38K$9.05B$233.36 - $500.570.01%
4552Viant Technology Inc.DSP$12.84+1.62%223.72K$271.27M$8.36 - $14.800.00%
4553Johnson & JohnsonJNJ$276.28+1.43%5.23M$665.08B$185.12 - $282.010.02%
4554MillerKnoll, Inc.MLKN$21.48-2.27%137.51K$1.48B$13.77 - $24.710.03%
4555Trustco Bank Corp NYTRST$57.36+1.50%93.09K$976.76M$37.66 - $59.960.03%
4556Rubrik, Inc.RBRK$105.82+0.25%3.04M$17.71B$42.25 - $139.920.00%
4557Semtech Corp.SMTC$103.43+12.89%3.53M$9.65B$60.28 - $201.990.00%
4558The E.W. Scripps CompanySSP$3.04+2.88%1.68M$245.03M$1.92 - $5.390.00%
4559Tyra Biosciences, Inc.TYRA$21.15+1.24%760.03K$1.26B$13.35 - $40.650.00%
4560Marriott InternationalMAR$416.50-0.19%1.03M$108.61B$279.87 - $433.300.01%
4561Palo Alto Networks, Inc.PANW$313.78-0.28%5.21M$256.92B$139.57 - $432.320.00%
4562Seneca Foods Corp.SENEA$150.61+5.28%80.95K$784.91M$99.58 - $210.000.00%
4563NetApp, Inc.NTAP$169.07-0.13%1.69M$33.21B$93.69 - $240.870.01%
4564Labcorp Holdings Inc.LH$366.65+0.90%425.24K$29.74B$244.52 - $373.340.01%
4565Nutex Health Inc.NUTX$181.00-6.84%155.63K$1.24B$83.99 - $226.160.01%
4566Venture Global, Inc.VG$11.52+1.06%11.19M$32.50B$5.72 - $17.620.01%
4567Design Therapeutics, Inc.DSGN$10.22+5.58%273.89K$639.33M$6.23 - $17.250.00%
4568Bassett Furniture Industries IBSET$21.74-1.56%55.47K$188.08M$13.17 - $23.600.03%
4569Guardian Pharmacy Services, Inc.GRDN$42.38+6.32%1.01M$2.11B$26.34 - $48.330.00%
4570Ponce Financial Group, Inc.PDLB$21.69-0.69%61.86K$524.64M$14.51 - $22.930.00%
4571Anika Therapeutics Inc.ANIK$14.51-24.83%278.77K$194.12M$9.01 - $22.880.00%
4572Whitehawk Therapeutics, Inc.WHWK$3.13+3.31%168.36K$178.15M$1.97 - $5.500.00%
4573Private Bancorp of America, Inc.PBAM$84.69+0.44%35.25K$485.25M$55.12 - $92.090.00%
4574SKK Holdings LimitedSKK$6.07+2.02%46.71K$21.59M$1.61 - $17.950.00%
4575QuinStreet, Inc.QNST$20.66+1.70%1.23M$1.18B$10.29 - $22.430.00%
4576Travere Therapeutics, Inc.TVTX$49.62+1.58%840.35K$4.68B$22.59 - $68.730.00%
4577Orchestra BioMed Holdings, Inc.OBIO$5.68+1.25%1.52M$341.64M$3.46 - $6.500.00%
4578The Vita Coco Company, Inc.COCO$62.41-1.93%824.21K$3.56B$40.62 - $85.830.00%
4579Entegris Inc.ENTG$127.90+2.71%3.58M$19.54B$67.97 - $186.940.00%
4580Kosmos Energy Ltd.KOS$2.10-2.73%13.93M$1.25B$0.84 - $3.340.00%
4581US Foods Holding Corp.USFD$106.66-0.17%1.68M$23.07B$69.88 - $112.560.00%
4582Plains GP Holdings, L.PPAGP$25.79-2.31%4.05M$5.10B$17.18 - $28.960.06%
4583River City BankRCBC$58.40-0.03%45.87K$829.29M$38.76 - $61.450.00%
4584Edgewell Personal Care CompanyEPC$27.97-2.00%234.68K$1.29B$15.72 - $30.360.02%
4585FormFactor Inc.FORM$81.18+13.10%1.53M$6.33B$47.33 - $160.270.00%
4586Sirius XM Holdings, Inc.SIRI$32.39-2.53%5.79M$10.90B$19.77 - $33.760.03%
4587BRC Group Holdings, Inc.RILYT$18.68-1.37%19.25K$0$10.35 - $22.200.00%
4588Relmada Therapeutics, Inc.RLMD$3.91+3.58%986.23K$417.19M$2.42 - $8.000.00%
4589TechnipFMC plcFTI$63.52+3.13%2.31M$24.70B$41.73 - $80.700.00%
4590Grid Dynamics Holdings, Inc.GDYN$13.10-3.29%1.38M$1.05B$5.11 - $14.020.00%
4591Diodes Inc.DIOD$77.64+13.52%778.54K$3.58B$42.28 - $125.990.00%
4592Farmers & Merchants Bancorp, Inc.FMAO$36.38-0.36%29.38K$500.69M$22.91 - $38.330.02%
4593CBL & Associates Properties, Inc.CBL$47.20-1.29%197.76K$1.46B$30.98 - $60.400.04%
4594Parke Bancorp Inc.PKBK$32.50+0.66%23.75K$382.28M$21.10 - $35.700.02%
4595Codere Online Luxembourg, S.A.CDRO$8.55+2.35%32.68K$388.59M$5.18 - $10.260.00%
4596SOPHiA GENETICS SASOPH$7.12+7.40%590.09K$597.42M$3.83 - $8.980.00%
4597Franklin Financial Services CorporationFRAF$69.49+0.27%53.86K$312.67M$45.16 - $73.690.02%
4598Krystal Biotech, Inc.KRYS$300.57+0.19%177.27K$8.90B$192.52 - $382.540.00%
4599Northeast BankNBN$126.45+1.32%79.27K$1.14B$80.75 - $142.310.07%
4600Superior Group of Companies, Inc.SGC$13.46-1.77%24.08K$214.67M$8.30 - $14.590.04%

Anthropic (PRE): Win NVIDIA H200

Claim PRE points for guaranteed prizes up to $3K

Anthropic (PRE): Win NVIDIA H200

Trade U.S. stocks Your Way on MEXC

RealStocksTokenized StocksStock Futures
What it isRealStocks — real shares of U.S.-listed companiesBlockchain-based tokens linked to U.S. stocks/ETFsUSDT-margined futures on U.S. stock price movements
OwnershipYes — actual sharesNo — synthetic exposure onlyNo — derivative exposure only
Shareholder rightsYes (e.g. dividends)NoNo
Trading hoursU.S. market sessions (pre-market, regular, after-hours, overnight)24/7Up to 24/7 (supported pairs)
Position typesBuy and holdBuy and holdLong, short, leveraged
Best forLong-term investors seeking ownership and dividend incomeTraders wanting round-the-clock access to stock exposure without holding sharesActive/short-term traders looking to speculate or hedge with leverage

Why Trade U.S. stocks on MEXC?

RealStocks, Real Ownership

Buy real US-listed shares through MEXC's partner licensed broker and receive applicable shareholder benefits, including dividends.

7,000+ U.S. stocks & ETFs

Access 7,000+ US-listed stocks and ETFs across technology, finance, healthcare, consumer sectors, and more.

Seamless USDT-to-Stock Access

Transfer USDT and convert between USDT and USD to fund your RealStocks account with ease.

Lower-Cost Stock Trading

Trade real U.S. stocks with competitive costs and keep more capital available for your investment strategy.

Frequently Asked Questions (FAQ)

What are 52-week top losing U.S. stocks?
These are U.S. stocks that have recorded some of the largest price declines over the past 52 weeks.
How is the 52-week decline measured?
It compares the latest available stock price with its price around 52 weeks earlier and calculates the percentage change.
Which stock has fallen the most over 52 weeks?
Littelfuse Inc. (LFUS) currently shows a 52-week decline of 47.66% as of 2026-11-06 21:45 UTC.
Why track 52-week stock losers?
The ranking helps identify stocks facing prolonged price weakness and provides a starting point for further company and valuation research.
Is a 52-week loser automatically a value stock?
No. A lower stock price does not necessarily mean a company is undervalued, so valuation and fundamental data should be reviewed separately.
How is this different from Top Losers?
52-Week Losers measures longer-term performance, while Top Losers focuses on shorter-term market declines.

Discover Top US Stocks

Disclaimer

US stock prices, indices, rankings, charts, and other market data displayed on this page may be sourced from third-party providers and may be delayed or inaccurate. MEXC provides this information for informational and educational purposes only and does not guarantee its accuracy or completeness. Nothing on this page constitutes financial or investment advice or a recommendation to buy or sell any security. US stock trading involves risk, and past performance does not guarantee future results. Users should conduct independent research before making investment decisions.