52-Week Top Gaining U.S. stocks
Track U.S. stocks with the strongest price gains over the past 52 weeks on MEXC. Stocks are ranked by their 52-week percentage change to highlight leading one-year performers.

Market Overview
U.S. stocks are mixed today. The Dow Jones is -0.46%, the S&P 500 is +0.31%, and the Nasdaq Composite is +1.09%. Across individual stocks, 2,319 are advancing while 2,800 are declining, suggesting a mixed market tone.
52 Week Gainers
| # | Stock | 52 Week Range | |||||
|---|---|---|---|---|---|---|---|
| 4251 | Figma, Inc.FIG | $18.83 | +2.06% | 11.44M | $11.80B | $16.60 - $45.42 | 0.00% |
| 4252 | RYTHM, Inc.RYM | $15.84 | +1.05% | 5.04K | $34.51M | $14.00 - $50.38 | 0.00% |
| 4253 | Exyn Technologies, Inc.EXYN | $2.21 | +6.13% | 56.74K | $18.14M | $1.50 - $7.20 | 0.00% |
| 4254 | Senstar Technologies CorporationSNT | $1.89 | +45.38% | 6.03M | $44.07M | $1.28 - $4.95 | 0.00% |
| 4255 | Forge Nano Holdings Inc.NANO | $4.28 | +5.17% | 194.87K | $532.63M | $3.12 - $11.96 | 0.00% |
| 4256 | Pyxis Oncology, Inc.PYXS | $1.66 | +2.48% | 505.38K | $197.91M | $1.03 - $5.55 | 0.00% |
| 4257 | Solo Brands, Inc.SBDS | $0.00 | 0.00% | 0 | $0 | $1.40 - $12.36 | 0.00% |
| 4258 | Ribbon Communications Inc.RBBN | $1.33 | -2.90% | 978.20K | $239.20M | $1.28 - $3.41 | 0.00% |
| 4259 | Spero Therapeutics, Inc.SPRO | $1.03 | +1.47% | 181.18K | $60.27M | $0.96 - $3.08 | 0.00% |
| 4260 | Grande Group LimitedGRAN | $1.16 | -4.39% | 10.00K | $29.98M | $0.78 - $5.91 | 0.00% |
| 4261 | Gyrodyne, LLCGYRO | $4.04 | -0.50% | 3.14K | $8.88M | $3.95 - $9.80 | 0.00% |
| 4262 | Franklin Wireless Corp.FKWL | $2.12 | -4.48% | 44.94K | $24.92M | $2.08 - $5.19 | 0.02% |
| 4263 | Airship AI Holdings, Inc.AISP | $1.79 | +2.87% | 331.00K | $61.65M | $1.69 - $4.42 | 0.00% |
| 4264 | Optimum Communications, Inc.OPTU | $0.75 | +31.69% | 6.04M | $204.42M | $0.48 - $2.14 | 0.00% |
| 4265 | Aprea Therapeutics, Inc.APRE | $0.52 | +2.02% | 64.48K | $6.48M | $0.41 - $1.49 | 0.00% |
| 4266 | Cognition Therapeutics, Inc.CGTX | $0.69 | +6.00% | 277.02K | $65.61M | $0.55 - $1.82 | 0.00% |
| 4267 | Canton Strategic Holdings, Inc.CNTN | $2.06 | +6.74% | 677.48K | $163.75M | $1.66 - $5.26 | 0.00% |
| 4268 | VirnetX Holding Corp.VHC | $9.54 | +0.46% | 5.04K | $40.03M | $8.41 - $25.83 | 0.00% |
| 4269 | Huadi International Group Co., Ltd.HUDI | $0.50 | +1.98% | 76.26K | $7.16M | $0.33 - $1.67 | 0.00% |
| 4270 | INNIO N.V.INIO | $13.76 | +3.19% | 5.98M | $11.05B | $12.95 - $42.95 | 0.00% |
| 4271 | Biomea Fusion, Inc.BMEA | $0.57 | -3.47% | 1.76M | $41.03M | $0.54 - $2.24 | 0.00% |
| 4272 | eGain CorporationEGAN | $5.95 | +0.68% | 105.09K | $150.66M | $5.02 - $15.95 | 0.00% |
| 4273 | Digi Power X Inc.DGXX | $2.08 | +10.00% | 3.05M | $211.41M | $1.77 - $9.20 | 0.00% |
| 4274 | Annovis Bio, Inc.ANVS | $0.82 | +43.53% | 8.86M | $35.08M | $0.62 - $5.50 | 0.00% |
| 4275 | Obsidian Therapeutics, Inc.OBX | $13.91 | +44.74% | 2.05M | $678.88M | $9.60 - $49.97 | 0.00% |
| 4276 | ZOOZ Strategy Ltd.ZOOZ | $5.22 | +2.79% | 3.03K | $48.06M | $4.55 - $13.45 | 0.00% |
| 4277 | Ideal Power Inc.IPWR | $2.06 | -1.67% | 403.95K | $33.81M | $1.90 - $9.30 | 0.00% |
| 4278 | Inter & Co. Inc.INTR | $3.86 | +2.12% | 6.43M | $1.25B | $3.75 - $10.36 | 0.00% |
| 4279 | FBS Global LimitedFBGL | $2.22 | +6.73% | 3.25K | $2.85M | $2.04 - $14.00 | 0.00% |
| 4280 | Addentax Group Corp.ATXG | $2.75 | +10.00% | 30.87K | $3.24M | $2.08 - $9.55 | 0.00% |
| 4281 | National CineMedia, Inc.NCMI | $1.59 | -1.85% | 328.11K | $149.58M | $1.43 - $4.33 | 0.07% |
| 4282 | Regencell Bioscience Holdings LimitedRGC | $5.28 | +0.85% | 200.45K | $2.62B | $4.51 - $69.00 | 0.00% |
| 4283 | Zillow Group, Inc.Z | $29.57 | -2.39% | 3.32M | $5.24B | $26.67 - $77.07 | 0.00% |
| 4284 | Fair Isaac CorporationFICO | $704.68 | -0.40% | 546.47K | $15.22B | $586.05 - $1,858.91 | 0.00% |
| 4285 | Jayud Global Logistics LimitedJYD | $1.52 | -5.00% | 57.82K | $4.81M | $0.47 - $5.75 | 0.00% |
| 4286 | TSS, Inc.TSSI | $6.71 | +12.77% | 1.13M | $189.35M | $5.90 - $17.57 | 0.00% |
| 4287 | Intelligent Living Application Group Inc.ILAG | $1.90 | +5.92% | 1.03K | $3.94M | $1.70 - $7.19 | 0.00% |
| 4288 | Mineralys Therapeutics, Inc.MLYS | $15.33 | +0.66% | 1.14M | $1.36B | $14.91 - $47.65 | 0.00% |
| 4289 | Kyntra Bio, Inc.KYNB | $3.83 | +3.55% | 12.35K | $15.49M | $3.60 - $9.70 | 0.00% |
| 4290 | FMC CorporationFMC | $5.63 | -7.25% | 4.85M | $704.53M | $4.37 - $18.29 | 0.11% |
| 4291 | Skyline Builders Group Holding LimitedKAZR | $1.29 | +2.38% | 134.28K | $20.36M | $0.92 - $3.39 | 0.00% |
| 4292 | Coastal Financial CorporationCCB | $42.66 | -0.57% | 65.94K | $652.04M | $35.56 - $120.05 | 0.00% |
| 4293 | DeFi Development Corp.DFDV | $3.34 | +5.05% | 1.14M | $103.66M | $2.44 - $8.80 | 0.00% |
| 4294 | O-I Glass, Inc.OI | $5.16 | -4.08% | 2.11M | $794.96M | $4.83 - $16.91 | 0.00% |
| 4295 | Clene Inc.CLNN | $3.92 | -3.02% | 57.43K | $50.96M | $3.02 - $10.84 | 0.00% |
| 4296 | Powerlaw Corp.PWRL | $11.08 | +4.95% | 98.20K | $493.33M | $9.40 - $40.00 | 0.00% |
| 4297 | Burford Capital LimitedBUR | $3.59 | -9.34% | 1.89M | $787.43M | $2.86 - $10.10 | 0.07% |
| 4298 | JELD-WEN Holding, Inc.JELD | $1.04 | +0.99% | 1.22M | $89.89M | $0.93 - $3.27 | 0.00% |
| 4299 | Insight Molecular Diagnostics Inc.IMDX | $2.50 | +1.83% | 88.56K | $81.65M | $2.35 - $8.51 | 0.00% |
| 4300 | MARA Holdings, Inc.MARA | $6.34 | +8.00% | 32.74M | $2.45B | $5.69 - $16.62 | 0.00% |
Trade U.S. stocks Your Way on MEXC
| RealStocks | Tokenized Stocks | Stock Futures | |
|---|---|---|---|
| What it is | RealStocks — real shares of U.S.-listed companies | Blockchain-based tokens linked to U.S. stocks/ETFs | USDT-margined futures on U.S. stock price movements |
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| Position types | Buy and hold | Buy and hold | Long, short, leveraged |
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Frequently Asked Questions (FAQ)
What are 52-week top gaining U.S. stocks?
How is the 52-week gain calculated?
Which stock has gained the most over 52 weeks?
Why use a 52-week stock performance ranking?
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How is this different from the daily Top Gainers list?
Discover Top US Stocks
Disclaimer
US stock prices, indices, rankings, charts, and other market data displayed on this page may be sourced from third-party providers and may be delayed or inaccurate. MEXC provides this information for informational and educational purposes only and does not guarantee its accuracy or completeness. Nothing on this page constitutes financial or investment advice or a recommendation to buy or sell any security. US stock trading involves risk, and past performance does not guarantee future results. Users should conduct independent research before making investment decisions.






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