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52-Week Top Gaining U.S. stocks

Track U.S. stocks with the strongest price gains over the past 52 weeks on MEXC. Stocks are ranked by their 52-week percentage change to highlight leading one-year performers.

52-Week Top Gaining U.S. stocks

Market Overview

U.S. stocks are mixed today. The Dow Jones is ⁦-0.46%⁩, the S&P 500 is ⁦+0.32%⁩, and the Nasdaq Composite is ⁦+1.09%⁩. Across individual stocks, 2,296 are advancing while 2,821 are declining, suggesting a mixed market tone.

Dow Jones
51,286.21
Change
-236.85-0.46%
S&P 500
7,376.92
Change
+23.19+0.32%
Nasdaq Composite
24,579.425
Change
+264.428+1.09%
24H Gainers
2,296
24H Losers
2,821

52 Week Gainers

#Stock52 Week Range
4351UP Fintech Holding Ltd AmericanTIGR$3.91+4.13%2.15M$671.89M$3.61 - $11.350.00%
4352Centrus Energy Corp.LEU$104.63+18.05%1.19M$2.01B$84.86 - $345.600.00%
4353Optimi Health Corp.OPTH$2.29-5.15%18.19K$13.09M$1.90 - $6.400.00%
4354D-Wave Quantum Inc.QBTS$10.67+17.90%23.48M$3.93B$8.48 - $32.390.00%
4355Comtech TelecommunicationsCMTL$1.14-2.54%222.84K$34.30M$1.14 - $6.210.00%
4356iHeartMedia, Inc.IHRT$1.76-5.61%676.02K$235.98M$1.38 - $6.560.00%
4357Intrusion Inc NewINTZ$0.65+3.09%225.03K$15.81M$0.47 - $1.800.00%
4358Metalpha Technology Holding LimitedMATH$1.01+0.48%46.05K$48.25M$0.73 - $3.190.00%
4359Biote Corp.BTMD$1.06+0.95%49.64K$30.40M$0.99 - $2.980.03%
4360Hydrofarm Holdings Group, Inc.HYFM$0.81+13.95%183.44K$3.92M$0.50 - $3.200.00%
4361HIVE Digital Technologies LtdHIVE$1.77+8.90%9.72M$490.30M$1.58 - $5.340.00%
4362Terra Innovatum Global N.V.NKLR$2.35+16.26%226.27K$253.60M$1.93 - $7.920.00%
4363Lucid Diagnostics Inc.LUCD$0.40+2.03%1.24M$80.89M$0.30 - $1.630.00%
4364AEye, Inc.LIDR$0.86-2.44%1.54M$40.28M$0.77 - $3.050.00%
4365BIO-key International, Inc.BKYI$2.36+1.69%65.80K$4.80M$1.55 - $13.800.00%
4366Genelux CorporationGNLX$1.97+8.79%312.15K$89.18M$1.77 - $7.500.00%
4367Pluri Inc.PLUR$1.21+1.43%2.71K$15.22M$0.85 - $4.870.00%
4368Natural Alternatives International Inc.NAII$1.08-0.92%11.60K$6.76M$1.06 - $4.960.00%
4369MNTN, Inc.MNTN$5.33+13.62%3.38M$727.83M$4.61 - $14.890.00%
4370Bragg Gaming Group Inc.BRAG$0.77-5.50%127.13K$23.47M$0.72 - $2.740.00%
4371Outlook Therapeutics, Inc.OTLK$0.44-0.64%1.61M$106.14M$0.16 - $2.540.00%
4372Atlas Lithium CorporationATLX$1.64-2.68%194.92K$48.25M$1.51 - $6.720.00%
4373Claritev CorporationCTEV$22.75+12.31%151.54K$385.52M$11.50 - $73.680.00%
4374Xerox Holdings CorporationXRX$1.10-2.21%12.10M$145.10M$1.05 - $3.780.19%
4375Cellectar Biosciences INC NEWCLRB$1.26+10.43%73.50K$11.88M$1.11 - $4.700.00%
4376Stewards, Inc.SWRD$2.56-11.13%328.06K$540.97M$1.46 - $7.500.00%
4377SenesTech, Inc.SNES$1.11-0.43%65.14K$6.02M$0.55 - $3.610.00%
4378Invivyd, Inc.IVVD$0.56-4.10%2.15M$165.65M$0.53 - $3.070.00%
4379Solana CompanyHSDT$1.94+0.26%580.32K$117.95M$1.19 - $5.770.00%
4380Lumen Technologies, Inc.LUMN$3.98+0.13%15.29M$4.11B$3.83 - $11.430.00%
4381InspireMD, Inc.NSPR$0.71-3.85%342.27K$33.05M$0.43 - $2.220.00%
4382American Battery Technology CompanyABAT$1.33+11.30%2.29M$190.34M$1.14 - $5.330.00%
4383PicS N.VPICS$6.87-2.96%557.59K$866.94M$6.42 - $19.950.00%
4384GSI TechnologyGSIT$3.01-5.78%1.16M$115.80M$2.98 - $13.000.00%
4385Sound Point Meridian Capital, Inc.SPMC$5.90+6.18%12.69K$120.87M$5.43 - $16.750.00%
4386Coincheck Group N.V.CNCK$1.27-0.78%9.47K$243.58M$1.20 - $9.310.00%
4387XCEL BRANDS INC.XELB$0.39+5.46%36.39K$2.67M$0.27 - $2.470.00%
4388Outset Medical, Inc.OM$4.22+2.44%36.76K$79.31M$2.84 - $12.480.00%
4389Mobilicom LimitedMOB$2.16-8.86%231.75K$38.47M$2.14 - $9.780.00%
4390X-Energy, Inc.XE$10.42+15.83%6.49M$3.16B$8.68 - $37.100.00%
4391Everbright Digital Holding LimitedEDHL$6.11+0.33%307.81K$9.80M$2.00 - $18.080.00%
4392Nexus Advanced Technologies Inc.NXAT$0.47+3.35%279.05K$1.28M$0.33 - $1.500.00%
4393NeOnc Technologies Holdings, Inc.NTHI$3.50+10.00%196.96K$91.68M$2.50 - $12.000.00%
4394Dare Bioscience, Inc.DARE$0.64-0.21%52.55K$12.65M$0.61 - $3.780.00%
4395Alnylam Pharmaceuticals, Inc.ALNY$155.94-0.46%2.33M$20.89B$154.66 - $479.790.00%
4396Local Bounti CorporationLOCL$0.87-3.88%8.99K$20.25M$0.86 - $3.130.00%
4397QT Imaging Holdings, Inc.QTI$2.11+0.97%27.50K$29.01M$1.99 - $7.600.00%
4398Powerus CorporationPUSA$1.52+5.90%456.89K$257.14M$1.35 - $6.570.00%
4399Cardiff Oncology, Inc.CRDF$0.79+4.70%339.35K$61.54M$0.75 - $3.310.00%
4400Medical Properties Trust, Inc.MPT$1.80-3.72%16.68M$1.08B$1.80 - $6.470.17%

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Frequently Asked Questions (FAQ)

What are 52-week top gaining U.S. stocks?
These are U.S. stocks with some of the strongest price gains over the past 52 weeks, providing a view of longer-term stock performance.
How is the 52-week gain calculated?
It compares a stock's latest available price with its price roughly 52 weeks earlier and expresses the change as a percentage.
Which stock has gained the most over 52 weeks?
UP Fintech Holding Ltd American (TIGR) currently leads with a 52-week gain of 62.26% as of 2026-11-06 22:01 UTC.
Why use a 52-week stock performance ranking?
It helps users identify stocks with sustained price strength over a longer period rather than focusing only on daily market moves.
Does strong 52-week performance guarantee future gains?
No. Historical stock performance does not determine future returns and should be considered alongside company fundamentals and current market conditions.
How is this different from the daily Top Gainers list?
The 52-week ranking focuses on one-year performance, while Top Gainers highlights shorter-term price movements.

Discover Top US Stocks

Disclaimer

US stock prices, indices, rankings, charts, and other market data displayed on this page may be sourced from third-party providers and may be delayed or inaccurate. MEXC provides this information for informational and educational purposes only and does not guarantee its accuracy or completeness. Nothing on this page constitutes financial or investment advice or a recommendation to buy or sell any security. US stock trading involves risk, and past performance does not guarantee future results. Users should conduct independent research before making investment decisions.