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52-Week Top Gaining U.S. stocks

Track U.S. stocks with the strongest price gains over the past 52 weeks on MEXC. Stocks are ranked by their 52-week percentage change to highlight leading one-year performers.

52-Week Top Gaining U.S. stocks

Market Overview

U.S. stocks are mixed today. The Dow Jones is ⁦-0.46%⁩, the S&P 500 is ⁦+0.32%⁩, and the Nasdaq Composite is ⁦+1.09%⁩. Across individual stocks, 2,308 are advancing while 2,809 are declining, suggesting a mixed market tone.

Dow Jones
51,286.21
Change
-236.85-0.46%
S&P 500
7,376.92
Change
+23.19+0.32%
Nasdaq Composite
24,579.425
Change
+264.428+1.09%
24H Gainers
2,308
24H Losers
2,809

52 Week Gainers

#Stock52 Week Range
4601Lightbridge Corp.LTBR$4.20+5.14%1.00M$157.25M$3.90 - $23.500.00%
4602J-Star Holding Co., LtdYMAT$1.06-2.75%63.10K$4.93M$0.85 - $13.000.00%
4603Circle8 Group, Inc.CIRC$0.19-3.12%976.56K$22.68M$0.18 - $0.980.00%
4604OBOOK Holdings Inc.OWLS$2.20-1.83%63.46K$201.40M$1.36 - $9.730.00%
4605Advanced Biomed Inc.ADVB$2.04-5.42%7.71K$3.37M$1.80 - $24.230.00%
4606DocGo Inc.DCGO$0.25+1.64%332.30K$24.53M$0.21 - $1.170.00%
4607Xanadu Quantum Technologies LimitedXNDU$2.67+12.18%3.44M$818.82M$2.34 - $42.440.00%
4608SharonAI Holdings, Inc.SHAZ$21.80+11.55%2.93M$777.69M$16.55 - $97.480.00%
4609Tevogen Inc.TVGN$5.38-1.53%36.85K$84.74M$3.64 - $27.410.00%
4610Swarmer, Inc.SWMR$7.11+3.80%460.96K$131.79M$6.51 - $83.300.00%
4611Kestrel Group, Ltd.KG$4.32+1.41%6.52K$33.02M$3.84 - $22.970.00%
4612Research Frontiers Inc.REFR$0.36-1.00%34.47K$12.69M$0.33 - $2.100.00%
4613Tactical Resources Corp.TREO$1.63-11.23%15.32K$22.46M$1.40 - $9.200.00%
4614EUDA Health Holdings LimitedEUDA$13.71-6.64%28.54K$41.07M$5.26 - $71.200.00%
4615Investcorp Credit Management BDC, Inc.ICMB$0.62-0.27%32.91K$8.90M$0.59 - $3.120.42%
4616Pasqal Holding SAPSQL$4.32+4.99%586.18K$1.13B$4.11 - $24.690.00%
4617WEBUY GLOBAL LTDWBUY$0.49-1.59%55.27K$2.56M$0.49 - $4.960.00%
4618Odyssey Marine Exploration, Inc.OMEX$10.85-1.45%23.68K$26.29M$9.59 - $66.750.00%
4619Atlas Critical Minerals CorporationATCX$1.99+0.76%4.04K$8.77M$1.85 - $14.010.00%
4620Intelligent Group LimitedINTJ$2.48+2.50%35.02K$4.27M$2.31 - $12.520.00%
4621Exicure, Inc.XCUR$0.95+7.30%17.62K$6.25M$0.80 - $9.480.00%
4622Aclarion, Inc.ACON$1.68+1.64%15.20K$4.83M$1.47 - $9.360.00%
4623NervGen Pharma Corp.NGEN$1.33+1.52%425.20K$107.16M$1.28 - $6.300.00%
4624Z Squared Inc.ZSQR$3.37+0.30%170.15K$178.82M$2.11 - $18.800.00%
4625Globavend Holdings LimitedGVH$1.00+0.50%24.98K$4.33M$0.77 - $6.460.00%
4626Oklo Inc.OKLO$23.56+22.20%23.29M$4.38B$18.54 - $120.950.00%
4627Imunon, Inc.IMNN$0.87-7.76%88.23K$4.90M$0.81 - $4.380.00%
4628Byrna Technologies, Inc.BYRN$3.83+1.87%202.11K$89.52M$3.17 - $20.690.00%
4629Sow Good Inc.SOWG$2.19-0.89%6.10K$44.00M$1.04 - $15.900.00%
4630WF International LimitedWXM$2.16+9.95%68.71K$6.73M$1.27 - $12.800.00%
4631Opendoor Technologies Inc.OPEN$1.40-22.35%64.23M$1.35B$1.38 - $9.150.00%
4632Aurelion Inc.AURE$0.93-2.46%289.20K$18.05M$0.85 - $5.480.00%
4633SEALSQ Corp.LAES$1.31+6.50%3.56M$251.86M$1.20 - $6.520.00%
4634Alpha Compute Corp.ALP$3.04+3.22%14.63K$4.70M$2.78 - $27.900.00%
4635Upland Software, Inc.UPLD$3.98-0.76%71.48K$11.76M$2.75 - $21.500.00%
4636ZeroStack Corp.ZSTK$2.54-1.17%3.26K$55.42M$1.32 - $15.040.00%
4637Filana Therapeutics, Inc.FLNA$0.45-1.97%599.17K$21.74M$0.42 - $2.270.00%
4638Pulsenmore Ltd.PLSM$1.58-1.93%6.61K$9.95M$1.48 - $12.970.00%
4639Tantech Holdings LtdTANH$12.54-9.21%73.04K$9.77M$8.01 - $60.000.00%
4640Surf Air Mobility Inc.SRFM$0.71+1.43%3.20M$87.29M$0.46 - $3.730.00%
4641Acurx Pharmaceuticals, Inc.ACXP$1.06+12.61%116.32K$5.92M$0.95 - $7.540.00%
4642Creative Medical Technology Holdings, Inc.CELZ$0.63+5.00%100.65K$4.15M$0.59 - $4.720.00%
4643Prairie Operating CoPROP$0.39-3.81%1.06M$43.88M$0.32 - $2.550.00%
4644First Breach Inc.FBDT$0.88+1.13%136.08K$53.56M$0.61 - $12.000.00%
4645mF International LimitedMFI$4.96-9.95%5.72K$243.36M$4.42 - $26.860.00%
4646Shuttle Pharmaceuticals Holdings, Inc.SHPH$5.35+6.01%10.30K$25.48M$2.58 - $44.400.00%
4647SANGRIX INC.SGRX$0.44-26.42%1.18M$2.75M$0.31 - $3.440.00%
4648Organogenesis Holdings Inc.ORGO$0.81-3.08%868.80K$104.74M$0.73 - $7.080.00%
4649Caribou Biosciences, Inc.CRBU$0.45+5.82%1.31M$47.81M$0.40 - $2.490.00%
4650Defi Technologies, Inc.DEFT$0.34-2.33%1.89M$130.87M$0.33 - $1.790.00%

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Frequently Asked Questions (FAQ)

What are 52-week top gaining U.S. stocks?
These are U.S. stocks with some of the strongest price gains over the past 52 weeks, providing a view of longer-term stock performance.
How is the 52-week gain calculated?
It compares a stock's latest available price with its price roughly 52 weeks earlier and expresses the change as a percentage.
Which stock has gained the most over 52 weeks?
Lightbridge Corp. (LTBR) currently leads with a 52-week gain of 76.66% as of 2026-11-06 21:49 UTC.
Why use a 52-week stock performance ranking?
It helps users identify stocks with sustained price strength over a longer period rather than focusing only on daily market moves.
Does strong 52-week performance guarantee future gains?
No. Historical stock performance does not determine future returns and should be considered alongside company fundamentals and current market conditions.
How is this different from the daily Top Gainers list?
The 52-week ranking focuses on one-year performance, while Top Gainers highlights shorter-term price movements.

Discover Top US Stocks

Disclaimer

US stock prices, indices, rankings, charts, and other market data displayed on this page may be sourced from third-party providers and may be delayed or inaccurate. MEXC provides this information for informational and educational purposes only and does not guarantee its accuracy or completeness. Nothing on this page constitutes financial or investment advice or a recommendation to buy or sell any security. US stock trading involves risk, and past performance does not guarantee future results. Users should conduct independent research before making investment decisions.